Perspectives on Clinical and Translational Research

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CTRSU Journal Club, November 21, 2014

Howdy Partners.  In this week’s journal club, I reviewed one of my most despised published papers of all time: Effect of daily chlorhexidine bathing on hospital-acquired infection by Climo et.al NEJM 2013, 368(6); 533-542. Boy, this is a terribly done study.  Aside from the clear issues with scientific writing (objective doesn’t match methods, which do…

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BreakoutDetection: Using the new Twitter tool for influenza surveillance

Hey world!  It’s been a while.  Regardless… The ingenious duders over at Twitter recently released their BreakoutDetection tool (https://blog.twitter.com/2014/breakout-detection-in-the-wild) to evaluate anomalies and mean shifts in large time-series datasets.  The first thing that came to my mind was: will this work for outbreak detection?  Of course, it should – I regularly use statistical process control…

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Data visualization – do we need a new paradigm in academic publishing?

Over the past few months I have been doing a lot of reading about data visualization because we are building dashboards for our clinical research enterprise.  Essentially these dashboards will provide real-time or near real-time metrics for our operation. For example, we will have a dashboard for each of our studies that outlines the number…

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Open Access – is it the devil?

Tim again – The journal Science recently published an article titled “Who’s afraid of peer review?” which centers on the issues related to the open access publication system.  This post will focus on the review process and the results of the Science article. Anyone who conducts research knows how the peer review process works.  Essentially it is…

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Academic Research for MDs – Choosing a Study Design

Hi again: In my last post I laid out how to construct a research question. Once you have a clear study question the next step is figuring out how you are going to answer that question. For this you need to determine the appropriate study design for your project. In this post I’ll go through…

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5 Questions to Ask Yourself Before Investing in a Website

Typically when someone asks for a website to be created or redesigned, they see it as a task that can be performed magically by the geeks over in IT.  While it takes a great deal of practice for the web developer to become ideal for this task, there is also a great deal of input…

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The Meaning of Life…

Hello all, it’s EBP again, I’m sure my title caught your attention, or at least made you stop and think “okay, who does this EBP think she is???”. But don’t be haters because I am going to talk about the meaning of life. In any case, I will move things along here and just say…

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The importance of a data analysis request system/pipeline

Hi all – Rob here. Today I wanted to write about processing data analysis requests. For a small organization with maybe one analyst/statistician a formal system for handling requests may not be necessary.  However, as the organization grows, multiple investigators with multiple lines of research may need several different analyses from several different data sets….

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Statistical software… Excel?

Hey pals, its Tim again — we made it through all of our CTRSC staff and have come full circle with the blog.  Now I actually have to have a real post. Here we go! The answer to the subject line… Yes.  If you are in the old school group that thinks Excel is for…

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Life from Synthetic to Real Data.

Dear Researchers I am a post-doctoral research fellow at Clinical and Translational Research Support Center. In this post I would like to shed some light on the idea of research in contemporary sciences.  Most of the research done now days is data driven. The million dollar question is how to get the data. In the…

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